Monday, May 18, 2020
Consequences And Development Of The DNA And The Polymerase...
We start with a piece of DNA to the direction of 3ââ¬â¢ to 5ââ¬â¢ strand of DNA is called the template strand. Initiation begins at the promoter region or the consensus sequences. The promoter region of the DNA is at the beginning of the gene. Two important finding regions occur at 10 base pairs and 35 base pairs upstream of transcription. Both sequences are important as mutations can prevent initiation. Common in Bacteria is the -10 region also known as the pribnow box. It is a series of thymine and adenine residues. The pribnow box is important for the recognition of the promoter region, other -10 and -35 consensus sequences exist but are recognized in a different manner. Another important locator on the DNA strand is the initiation site orâ⬠¦show more contentâ⬠¦In a given cell order there are numerous types of sigma factors. Under normal condition or under stress different sigma factors recognize different promoter regions. Now that the holoenzyme is complete, the fo rmation of the transcription bubble can take place. The RNA polymerase unwinds the DNA by itself. In order to start transcription energy from a ATP or GTP is required, where the ribose from the triphosphate provides a 3ââ¬â¢ hydroxyl to attack the first phosphate in the first nucleotide, this displaces the pyrophosphate. The new RNA therefore has a triphosphate at its 5ââ¬â¢ end. Once transcription has started the sigma factor falls off. The next stage is elongation. Elongation occurs when approximately 12 nucleotides have been added to the RNA strand and the sigma subunit is dissociated and the polymerase has started to move from the promoter region. When the RNA is synthesized it is made in opposite polarity to the template DNA strand, meaning the 3ââ¬â¢ end of the RNA faces the same direction at the 5ââ¬â¢ end of the DNA. Inside the transcription bubble nucleotides come inside the RNA polymerase to make a complementary strand to the template strand of DNA. Here all base pairs match up like in DNA synthesis only instead of thymine uracil is paired with Adenine for RNA synthesis. Constant unwinding can lead to supercoiling of the DNA, which is like a telephone cord that is twisted at one end. Eventually stress in the middle ofShow MoreRelatedTypes And Types Of Tomato Production Essay1385 Words à |à 6 Pagesinterveinal areas, interveinal and marginal chlorosis and in some cases purple discolouration of the a baxial surface of the leaves. The disease induces severe stunting, development of small branches that causes bushy growth, reduced fruiting or partial to complete sterility if infection takes place at early stage of plant development. Based on biological properties and types of symptoms produced, tomato diseases caused by begomoviruses are called as ââ¬Ëleaf curlââ¬â¢ or ââ¬Ëyellow leaf curlââ¬â¢ disease. HoweverRead MoreNext Generation Sequencing Is The Method Of Determining The Order Of Nucleotides1362 Words à |à 6 PagesGENERATION SEQUENCING Introduction DNA sequencing is the method of determining the order of nucleotides in DNA. It includes the method that is used to determine the order of four bases -adenine, thymine, guanine and cytosine in DNA. DNA sequencing has greatly accelerated research and discovery in biological and medical field. The first DNA sequence was obtained using two-dimensional chromatography, in the early 1970s by academic researchers which was laborious. Now DNA sequencing has become easier andRead MoreThe Effects Of Uvb Waves On Dna Bases1157 Words à |à 5 Pagestypically reach the Earth ( Bianchi, J. et al. 2013). However, in many experiments UVC is used. What We Already Know on Effects of UVB Waves on DNA Bases. UVB radiation is the most energetic component of solar radiation that hits the earthââ¬â¢s surface. The main photochemical reactions within cellular DNA involve mostly the direct absorption of UVB photons by the DNA bases, mostly pyrimidine constituents, including thymine, cytosine and the minor 5-methylcytosine ( Bianchi, J. et al.). It was also shownRead MoreThe Use Of Adars And Other Forms Of Rna Editing And Their Potential For Revolutionize Biomarker Development984 Words à |à 4 PagesIntroduction Transposable elements (TEs) such as Arthrobacter luteus (Alu) sequences make up approximately 20% of the human DNA genome. The repeated DNA sequences were once thought to be ââ¬Å"junkâ⬠for decades after its discovery in the 1940s, however, recent data suggest that these sequences cause codon alteration and splice site relocation. Ultimately these events change the human genome. The transposable elements are believed to have risen from retrotransposition and constant RNA editing over evolutionRead MoreThe Applications Of Genetic Engineering1897 Words à |à 8 Pageslike the function and structure of genes. The increased development of technology has allowed plants, microbes and even animals to be genetically modified. Organisms are genetically engineered to discover the functions of certain genes. Other applications include transforming microorganisms such as bacteria cells with a gene coding for a useful protein. The use of vectors in Genetic Engineering A vector is known as being the length of DNA which has a role to carry the gene into the host cell.Read MoreEssay about Genetic Manipulation or Genetic Engineering952 Words à |à 4 Pagesthrough recombinant DNA technology, which involves either the combining of DNA from different genomes or the insertion of foreign DNA into a genome. The production of transgenic organisms, particularly animals, is a highly controversial topic and its advantages and disadvantages will be discussed thoroughly below. The process of recombinant DNA technology (recDNA) manipulates DNA by the use of restriction enzymes, ligases and PCR (polymerase chain reaction). Sections of DNA are cut using restrictionRead MoreThe Replication Of Dna By Escherichia Coli Essay1479 Words à |à 6 PagesMeselson and Stahl (Vol 4, 1958) includes a groundbreaking development into further understanding of DNA Replication. On pages 671 ââ¬â 682 is an article titled ââ¬Å"The Replication of DNA in Escherichia Coliâ⬠. Meselson and Stahl conducted an experiment to understand how DNA self-replicates by the use of Bacterial transformation to clone parental DNA. In the article, Meselson and Stahl investigate the distribution between the parental and daughter DNA molecules. This is achieved by the use of Radio IsotopicRead MoreCommon Genomic Variation Alone Cannot Account for Complex Traits2166 Words à |à 9 Pagesstems from the observation that genotypically identical cells can exhibit alternative and stably heritable phenotypes. These traits, along with the chromosomal mechanisms that produce them and ensure their propagation without alterations in the primary DNA sequence, are referred to as ââ¬Å"epigenetic.â⬠(7-9). Alternatively, regions in the genome where the epigenetic state varies and results in alternative phenotypes are referred to as ââ¬Å"epiallelesâ⬠(10). Epigenetic variation adds a regulatory layer to genomeRead MoreCell Biology Final Essay30093 Words à |à 121 Pages_______ in eukaryotic cells. A) ribosomes B) oxidative phosphorylation C) DNA molecules -D) a nucleus 2. Cytoplasmic organelles are - A) absent in prokaryotic cells; present in eukaryotic cells. B) present in both prokaryotic and eukaryotic cells. C) present in prokaryotic cells; absent in eukaryotic cells. D) absent in both prokaryotic and eukaryotic cells. 3. Eukaryotic chromosomes contain _______ DNA molecules. A) single linear B) single circular -C) multiple linear Read More Haemochromatosis Detection Essay2772 Words à |à 12 Pagesthyroid, pancreas, lungs, and synovium (joints). These organs cease to function adequately and eventually become diseased. Serious illnesses such as diabetes, cirrhosis, hepatoma, hypogonadotrophic hypogonadism, cardiomyopathy and arthritis may be a consequence of this disease . It affects one in every three hundred Caucasians, and one in nine is a carrier , hence, making its early detection vital. The gene responsible for HH (HLA-H) was recently identified on the short arm of chromosome 6 and is thought
Wednesday, May 6, 2020
Graduation Speech - 1128 Words
Sasenarine Tomby Graduation Speech 2011 Good afternoon [name of members of the head table], teachers, parents, students, fellow graduates and distinguished guests. I must first and foremost thank God for this blessing and honor to stand before you today as Valedictorian of the Class of 2011. Yet, today is not only my day to shine. Every graduate present here is deserving of high praise and recognition and I would like to congratulate each of you on reaching this milestone in life. I think I speak for my fellow graduates when I say that this is a moment we have always imagined and one we will remember for the rest of our lives. I come from a humble family where the values of hard work, persistence and drive are neverâ⬠¦show more contentâ⬠¦We are honored and grateful to have you as educators and to say we were once your students. Lastly, I would now like to take this time to thank my family for their endless support and love. Mom, thank you for your encouraging words, your advice, and for always believing in me even at times when I gave up on myself. Just as you have stood by me and helped me accomplish so many goals, I hope to be able to fulfill many of your dreams. To my little sister, thank you for keeping the child inside of me alive, for always finding a way to put a smile on my face, and for your honesty. Last but not least, I am proud to share this moment with my father, thank you for your support, guidance, and for the lifelong values and morals you have instilled in me, a person whose wisdom and spirituality I deeply admire. I am extremely grateful and thankful to be the first child in my family that my parents will witness graduate from secondary school. To my family, I may not say it enough, but I love you all more than words can express and without your presence in my life, I donââ¬â¢t know wh ere or who I would be. Maya Angelou said, ââ¬Å"But nobody, no nobody can make it out here aloneâ⬠and I think my fellow graduates will agree with me when I say that this moment would not have been possible for eachShow MoreRelatedGraduation Speech : My Graduation Essay1022 Words à |à 5 Pages My Graduation A Graduation ceremony is one of the major steps in life, it marks the start of new changes in our lives. It ushers us into growing up and be responsible for our actions. It marks a new dawn of embracing life experiences, cultivation of good work ethics and eventually culminates in chasing our dreams. On my graduation day, I woke up to the sweet aroma of the breakfast my sister was making. I sat down to eat when the food was ready. It took me about 2 hours to finishRead MoreGraduation Speech650 Words à |à 3 PagesCongratulations everyone, congratulations. If youre participating in this graduation ceremony, youve taken the next step toward your future goals and dreams. For those of you that just finished your transfer degrees, congratulations. To those of you that came back to school after a few years off to get a better education, congratulations. To those of you that came to get a certificate or learn IT or computer programming so you can get a better job, congratulations. Now that youre moving onRead More Graduation Speech Essay1010 Words à |à 5 PagesLadies, gentlemen, parents, friends, family, staff, fellow students: Instead of taking up more time and reading my speech, it is available to you at http://www.olenââ¬â¢s_speech.com. Thank you. No, just kidding. But seriously folks... Today we are gathered here to celebrate our graduation from 12 long years of schooling. The education granted to us has been a privilege. One so graciously given to us by the citizens of our state, by our community, and by our parents. Today would not beRead More Graduation Speech Essay1009 Words à |à 5 Pagesyou might ever sit through. Most of us, though, and I regret that I am in this group, will sit through many more ceremonies -- ceremonies longer and more tedious that this or anything else you can imagine. If you think this is bad, try a college graduation. Think, that is, attend a wedding. And, if just for a moment you think that that is bad, just be thankful you have never attended or will attend a Bar Mitzvah. The only ceremony I think anybody would truly enjoy attending is a funeral. But, onlyRead MoreEssay on Graduation Speech830 Words à |à 4 Pagesthe senior class president. A few weeks ago, I was told that I would be speaking at graduation. I was asked to put together a speech for tonight -- Ive become experienced at speech writing over the past couple of weeks. The speech that you are hearing is the fourth one Ive written, the recycle bin needs to be emptied at home and I need a new highlighter. Thank you, Mr. Mier, you get an A+ for your help as my speech teacher but an F for saving trees. Tonight Id like to talk to three groupsRead MoreAn Example of a Graduation Speech653 Words à |à 3 Pageswriting papers, doing homework, taking an occasional pop quiz, and of course taking countless exams, it is that time that we all anticipateâ⬠¦Graduation! Purpose Statement: Since the majority of us are seniors, and graduation is a little less than a month away, I am going to provide you with some historical background information and some fun facts about graduation in order to make the occasion even more meaningful than it already is. Road Map: Most of you could probably agree that high school wasRead More Graduation Speech Essay1516 Words à |à 7 Pagesstudy abroad, and with the great help of the Turner family, Ms. Joy Fitzpatrick who is the international student program coordinator, and my parents, I entered America as an international student on March 11, 2001, only one week after my high school graduation in Japan. It seems as though yesterday when I saw my host mom crying at the airport to see me landed to America safely, as if she were welcoming back her own daughter. I still recall the very first class I took. I was so scared and nervous thatRead More Graduation Speech Essay1115 Words à |à 5 Pagesthis graduation speech, several people suggested including a profound quote offering ââ¬Å"encouraging advice to the young graduatesâ⬠, and then there were others who said, ââ¬Å"eh donââ¬â¢t worry about it, no one listens to those anyway.â⬠Fortunately, I was actually able to take from both suggestions and found a happy balance. You see, I wonââ¬â¢t tell you today to: ââ¬Å"Dare to dreamâ⬠or ââ¬Å"Find your own visionâ⬠or even to ââ¬Å"Strive for excellence,â⬠or any trite clichà © thatââ¬â¢s ever been said in a graduation speech. SoRead More Graduation Speech Essay560 Words à |à 3 PagesWhen they were trying to find someone to give this speech they first asked the most intelligent, smart person they could find. But she turned them down. So then they asked the most beautiful, lovely, attractive person they could find. She also turned them down. Next they asked the nicest, sweetest, kindest, most sincere person they could find. Then I decided it would be rude to turn them down three times in a row, so here I am. How many people here like tomato soup? Come on, raise your hand ifRead More Graduation Speech Essay881 Words à |à 4 PagesAre you ready for the real world? Will I am ready, and I want to help you out. ... I want to pump you up! Tonight marks a turning point in our lives as young adults. This milestone of graduating with a high school education has come at last. And yet, knowledge does not exist solely in scholarly facts, but more so in the relationships and friendships that we have forged along the way. Albert Schweitzer once said, At times our own light goes out and is rekindled by a spark from another person. Each
Engineering Ethics free essay sample
Also several International Engineering Conferences had already considered Engineering ethics aiming to promote the profession. What does word Ethic mean? The study of standard of conduct and moral judgment. The code of morals of a particular person, religion, group, profession, etc. So, Ethics are very important for engineering profession and also engineers. Elements of Engineering Ethics Responsibility to society, clients and staff. Competence. Integrity. Impartiality. Corruption. In Engineering Profession Engineer must help in increasing effectiveness of engineering profession by exchange of information and experience with other engineers, and cooperation with all engineering societies, schools and scientific engineering journals. Engineer must not announce of his work and his peculiarities to obtain for himself credit and he must avoid everything which harms the profession. Engineer Relation with Public Recognition duties to society and environment. Respect laws, regulations, technical rules and standards. Respect the dignity, culture, religion, culture and customs of people. Increase public engineering information and must not encourage false lies related to engineering. We will write a custom essay sample on Engineering Ethics or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Take sufficient care of safety and health of public and staff. When asked to be a witness in from of a court justice or any official organization, he must not give his opinion except when he is sure it is based on sufficient information and correct belief. Not to issue false data or critics related to general policies for the benefits of specific side or asked to do it, or rented for it. Not to give opinion in engineering subject except has sufficient information and has known all facts related to the subject. Maintain knowledge and skills at levels consistent with developments in technology, legislation and management. Engineer Relation with Clients and Staff Apply due skill, care and diligence in the services rendered to the client. Perform services only when competent to perform them. Take responsibility for the services provided. Act in the legitimate interest of the client. Provide all services with integrity and faithfulness. Not disclose, without the consent of the client, business or technical secrets obtained in the services for that client. Be impartial in the provision of professional services, judgment or decisions. Inform the client of any potential conflict of interest related to the services to the client. Neither offer nor accept remuneration that seeks to influence fair business conduct. Engineer Relation with Clients and Staff Cont. Cooperate fully with any legitimately constituted investigative body which makes inquiry into the administration of any contract for services, supplies or construction. Abuse of public or private office for personal gain/profit. Corruption is more than stealing funds, it is stealing trust. Transparent procurement procedures should be used, based upon objective selection and award criteria. Many governments and international financing institutions are committed to the tackling of corrupt practices. Behave in technical matters to client or staff as honest agent and trustable one. Behave with honesty and justice in relations with staff and clients and between agents when supervising execution of contracts. Clarify position to clients and staff before starting any commitment. Take care of dangerous cases which threaten life and body. Engineer Relation with Clients and Staff Cont. Present clearly the consequences expected from any suggested deviation in engineering work responsible of its execution. Apply and give advice to clients and staff and cooperate with them. Not to disclose any information related to clients or staff commercially or technically without their consents. Not to accept any financial reward or others from more than one source for one service without the approval of all persons owners of this service. Not to accept any commissions or grant directly or by third party from contractors or other groups for work with client or staff related to the work. Not interfere financially in tenders as contractor or between contractors in work except with the approval of client or employer. Relations Between Engineers Protect engineering profession as a whole or individually from any misunderstanding or misinterpretation. Give credit of engineering work to person who deserve it. Emphasize the principle of sufficient reward and respectable to person performing engineering work. Find opportunities to promote and up grade engineers in service for their technical development. Not to harm the technical reputation of other engineer and his efforts directly or indirectly. In case parts of engineerââ¬â¢s work is not legal and honest forward these information to authorities to take actions. Not to replace other engineer employed in specific work. Not compete other engineer to get a job by decreasing normal salaries. Thank you
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